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Article

Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease.

Neurobiology of aging - 1 Sept 2014

Poirier Judes, Miron Justin, Picard Cynthia, Gormley Patrick, Théroux Louise, Breitner John, Dea Doris

Abstract excerpt

The discovery that the apolipoprotein E (apoE) ε4 allele is genetically linked to both sporadic and familial late-onset Alzheimer's disease (AD) raises the possibility that a dysfunction of the lipid transport system could seriously affect lipid homeostasis in the brain of AD subjects. The presen...

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Identifiers

PMID: 24973118
DOI: 10.1016/j.neurobiolaging.2014.03.037
PMCID: PMC5140289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24973118-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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