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Article

In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathology.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Handattu Shaila P, Monroe Candyce E, Nayyar Gaurav, Palgunachari Mayakonda N, Kadish Inga, van Groen Thomas, Anantharamaiah G M, Garber David W

Abstract excerpt

BACKGROUND: Apolipoprotein E (ApoE) is the major apolipoprotein present in the high-density lipoprotein-like particles in the central nervous system (CNS). ApoE is involved in various protective functions in CNS including cholesterol transport, anti-inflammatory, and antioxidant effects. An ApoE peptide would be expected to exert protective effects on neuroinflammation. OBJECTIVE: To determine the effects of an...

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Identifiers

PMID: 23603398
DOI: 10.3233/JAD-122377
PMCID: PMC4120251

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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