Article
The Kto-Skd complex can regulate ptc expression by interacting with Cubitus interruptus (Ci) in the Hedgehog signaling pathway.
The Journal of biological chemistry - 8 Aug 2014
Mao Feifei, Yang Xiaofeng, Fu Lin, Lv Xiangdong, Zhang Zhao, Wu Wenqing, Yang Siqi, Zhou Zhaocai, Zhang Lei, Zhao Yun
Abstract excerpt
The hedgehog (Hh) signaling pathway plays a very important role in metazoan development by controlling pattern formation. Drosophila imaginal discs are subdivided into anterior and posterior compartments that derive from adjacent cell populations. The anterior/posterior (A/P) boundaries, which are critical to maintaining the position of organizers, are established by a complex mechanism involving Hh signaling....
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