Article
Porcine Parkin: molecular cloning of PARK2 cDNA, expression analysis, and identification of a splicing variant.
Biochemical and biophysical research communications - 1 Sept 2006
Bjerre Ditte, Madsen Lone Bruhn, Bendixen Christian, Larsen Knud
Abstract excerpt
Parkin, encoded by the PARK2 gene, is an E3 ligase which functions as an integral component of the cytoplasmic ubiquitin/proteasomal protein degradation pathway. Mutations in the PARK2 gene, resulting in the loss of parkin function, leads to autosomal recessive juvenile Parkinsonism (AR-JP). This...
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