Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative splicing: multiple control mechanisms and involvement in human disease.

Trends in genetics : TIG - 1 Apr 2002

Cáceres Javier F, Kornblihtt Alberto R

Abstract excerpt

Alternative splicing is an important mechanism for controlling gene expression. It allows large proteomic complexity from a limited number of genes. An interplay of cis-acting sequences and trans-acting factors modulates the splicing of regulated exons. Here, we discuss the roles of the SR and hnRNP families of proteins in this process. We also focus on the role of the transcriptional machinery in the regulation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Gene Expression Regulation
Share to Heterogeneous-Nuclear Ribonucleoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Multigene Family

Share to Ribonucleoproteins

Share to RNA Splice Sites

Share to Trans-Activators

Share to Transcription, Genetic

Source

Identifiers

PMID: 11932019
DOI: 10.1016/s0168-9525(01)02626-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative splicing: multiple control mechanisms and involvement in human disease.PMID 11932019Read ↗

Functional roles of alternative splicing factors in human disease.Semantic proximity Read ↗

Genomics of alternative splicing: evolution, development and pathophysiology.Semantic proximity Read ↗

Function of alternative splicing.Semantic proximity Read ↗

Alternative Splicing in Genetic Diseases: Improved Diagnosis and Novel Treatment Options.Semantic proximity Read ↗

Alternative Splicing and Isoforms: From Mechanisms to DiseasesSemantic proximity Read ↗

The Role of Alternative Splicing in the Control of Immune Homeostasis and Cellular DifferentiationSemantic proximity Read ↗

[Alternative splicing--principles, functional consequences and therapeutic implications].Semantic proximity Read ↗

Mechanisms and Regulation of Alternative Pre-mRNA Splicing.Semantic proximity Read ↗

A genomic view of alternative splicing.Semantic proximity Read ↗

Splicing in disease: disruption of the splicing code and the decoding machinery.Semantic proximity Read ↗

Splicing, cis genetic variation and disease.Semantic proximity Read ↗

RNA Splicing: Regulation and Dysregulation in the Heart.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.