Article
Functional divergence of the miRNA transcriptome at the onset of Drosophila metamorphosis.
Molecular biology and evolution - 1 Oct 2014
Yeh Shu-Dan, von Grotthuss Marcin, Gandasetiawan Kania A, Jayasekera Suvini, Xia Xiao-Qin, Chan Carolus, Jayaswal Vivek, Ranz José M
Abstract excerpt
MicroRNAs (miRNAs) are endogenous RNA molecules that regulate gene expression posttranscriptionally. To date, the emergence of miRNAs and their patterns of sequence evolution have been analyzed in great detail. However, the extent to which miRNA expression levels have evolved over time, the role different evolutionary forces play in shaping these changes, and whether this variation in miRNA expression can reveal...
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