Article
Evolutionary relationships between miRNA genes and their activity.
BMC genomics - 22 Dec 2012
Zhu Yan, Skogerbø Geir, Ning Qianqian, Wang Zhen, Li Biqing, Yang Shuang, Sun Hong, Li Yixue
Abstract excerpt
BACKGROUND: The emergence of vertebrates is characterized by a strong increase in miRNA families. MicroRNAs interact broadly with many transcripts, and the evolution of such a system is intriguing. However, evolutionary questions concerning the origin of miRNA genes and their subsequent evolution remain unexplained. RESULTS: In order to systematically understand the evolutionary relationship between miRNAs gene...
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