Article
MicroRNA regulation and interspecific variation of gene expression.
Trends in genetics : TIG - 1 Aug 2007
Cui Qinghua, Yu Zhenbao, Purisima Enrico O, Wang Edwin
Abstract excerpt
MicroRNAs (miRNAs) modulate expression of their target genes in various tissues and at different developmental stages, but it is unclear whether they drive cross-species variation in gene expression. By comparing data from mammal and fly species we found that the cross-species expression variation of miRNA targets is significantly lower than that of other genes. This implies that miRNAs can affect gene expression...
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