Article
The evolution of animal microRNA function.
Current opinion in genetics & development - 1 Apr 2007
Niwa Ryusuke, Slack Frank J
Abstract excerpt
MicroRNAs (miRNAs) are a large class of small RNAs that function as negative gene regulators in eukaryotes. They regulate diverse biological processes, and bioinformatics data indicate that each miRNA can control hundreds of gene targets, underscoring the potential influence of miRNAs on almost every genetic pathway. In addition to the roles in ontogeny, recent evidence has suggested the possibility that miRNAs...
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