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Article

Genetic predictors of Stevens-Johnson syndrome and toxic epidermal necrolysis induced by aromatic antiepileptic drugs among the Chinese Han population.

Epilepsy & behavior : E&B - 1 Aug 2014

Wang Wei, Hu Fa-Yun, Wu Xin-Tong, An Dong-Mei, Yan Bo, Zhou Dong

Abstract excerpt

BACKGROUND: Previous studies suggested that one or more HLA alleles participate in the pathogenesis of AED-induced SJS/TEN, but most of these studies focused only on the HLA-B alleles. PURPOSE: The aim of this study was to investigate the pathogenesis of AED-induced SJS/TEN across a broader spectrum of HLA alleles, including the HLA-A, -B and -DRB1 alleles, to further explore the association between each HLA...

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Identifiers

PMID: 24949577
DOI: 10.1016/j.yebeh.2014.05.025

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