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Article

Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.

Pharmacogenomics - 1 Mar 2010

Hung Shuen-Iu, Chung Wen-Hung, Liu Zhi-Sheng, Chen Chien-Hsiun, Hsih Mo-Song, Hui Rosaline Chung-yee, Chu Chia-Yu, Chen Yuan-Tsong

Abstract excerpt

AIMS: Compared with other categories of drugs, such as antibiotics and NSAIDs, antiepileptic therapies are associated with a high incidence of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). We previously reported that carbamazepine (CBZ)-SJS/TEN is strongly associated with the HLA-B*1502 in Han Chinese, which has been confirmed in other Southeast Asian countries where the allele is...

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Identifiers

PMID: 20235791
DOI: 10.2217/pgs.09.162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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