Article
HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs.
Yonsei medical journal - 1 Jan 2016
Park Hye Jung, Kim Young Joo, Kim Dong Hyun, Kim Junho, Park Kyung Hee, Park Jung Won, Lee Jae Hyun
Abstract excerpt
PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction. SJS/TEN induced by certain drug is well known to be associated with some human leukocyte antigen (HLA) gene type. We aimed to explore HLA allele frequencies and their association with SJS/TEN according to culprit drugs in Korea. MATERIALS AND METHODS: We enrolled 5802...
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