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Article

Genetic predisposition of life-threatening antiepileptic-induced skin reactions.

Expert opinion on drug safety - 1 Jan 2010

Chung Wen-Hung, Hung Shuen-Iu, Chen Yuan-Tsong

Abstract excerpt

IMPORTANCE OF THE FIELD: Recent advances in pharmacogenetic studies have uncovered increasingly more genes that predispose individuals to adverse drug reactions. Aromatic antiepileptic drugs (AEDs) are a frequent cause of severe cutaneous adverse reactions (SCAR). A strong genetic association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20001755
DOI: 10.1517/14740330903427969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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