Article
Co-option of Sox3 as the male-determining factor on the Y chromosome in the fish Oryzias dancena.
Nature communications - 20 Jun 2014
Takehana Yusuke, Matsuda Masaru, Myosho Taijun, Suster Maximiliano L, Kawakami Koichi, Shin-I Tadasu, Kohara Yuji, Kuroki Yoko, Toyoda Atsushi, Fujiyama Asao, Hamaguchi Satoshi, Sakaizumi Mitsuru, Naruse Kiyoshi
Abstract excerpt
Sex chromosomes harbour a primary sex-determining signal that triggers sexual development of the organism. However, diverse sex chromosome systems have been evolved in vertebrates. Here we use positional cloning to identify the sex-determining locus of a medaka-related fish, Oryzias dancena, and find that the locus on the Y chromosome contains a cis-regulatory element that upregulates neighbouring Sox3 expression...
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