Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autosomal gsdf acts as a male sex initiator in the fish medaka.

Scientific reports - 27 Jan 2016

Zhang Xi, Guan Guijun, Li Mingyou, Zhu Feng, Liu Qizhi, Naruse Kiyoshi, Herpin Amaury, Nagahama Yoshitaka, Li Jiale, Hong Yunhan

Abstract excerpt

Sex is pivotal for reproduction, healthcare and evolution. In the fish medaka, the Y-chromosomal dmy (also dmrt1bY) serves the sex determiner, which activates dmrt1 for male sex maintenance. However, how dmy makes the male decision via initiating testicular differentiation has remained unknown. Here we report that autosomal gsdf serves a male sex initiator. Gene addition and deletion revealed that gsdf was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Y Chromosome
Share to Gene Deletion
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Share to Gonads

Share to Oryzias

Share to Phenotype

Share to Sex Determination Processes

Source

Open in PubMed Open full text

Identifiers

PMID: 26813267
DOI: 10.1038/srep19738
PMCID: PMC4728440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autosomal gsdf acts as a male sex initiator in the fish medaka.PMID 26813267Read ↗

Sex determination in fish: Lessons from the sex-determining gene of the teleost medaka, Oryzias latipes.Semantic proximity Read ↗

Sex determination, gonadal sex differentiation, and plasticity in vertebrate speciesSemantic proximity Read ↗

DMY gene induces male development in genetically female (XX) medaka fish.Semantic proximity Read ↗

Dmy initiates masculinity by altering Gsdf/Sox9a2/Rspo1 expression in medaka (Oryzias latipes).Semantic proximity Read ↗

Evolution of DMY, a newly emergent male sex-determination gene of medaka fish.Semantic proximity Read ↗

DMY is a Y-specific DM-domain gene required for male development in the medaka fish.Semantic proximity Read ↗

<i>gsdf</i> is a downstream gene of <i>dmrt1</i> that functions in the male sex determination pathway of the Nile tilapiaSemantic proximity Read ↗

KDM6B is a conserved activator at the top of the male sex determination pathwaySemantic proximity Read ↗

Co-option of Sox3 as the male-determining factor on the Y chromosome in the fish Oryzias dancena.Semantic proximity Read ↗

Dmrt1 mutation causes a male-to-female sex reversal after the sex determination by Dmy in the medaka.Semantic proximity Read ↗

Mammalian sex determination: from gonads to brain.Semantic proximity Read ↗

Dmrt1 is required for primary male sexual differentiation in Chinese soft-shelled turtle Pelodiscus sinensisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.