Article
Tracing the emergence of a novel sex-determining gene in medaka, Oryzias luzonensis.
Genetics - 1 May 2012
Myosho Taijun, Otake Hiroyuki, Masuyama Haruo, Matsuda Masaru, Kuroki Yoko, Fujiyama Asao, Naruse Kiyoshi, Hamaguchi Satoshi, Sakaizumi Mitsuru
Abstract excerpt
Three sex-determining (SD) genes, SRY (mammals), Dmy (medaka), and DM-W (Xenopus laevis), have been identified to date in vertebrates. However, how and why a new sex-determining gene appears remains unknown, as do the switching mechanisms of the master sex-determining gene. Here, we used positional cloning to search for the sex-determining gene in Oryzias luzonensis and found that GsdfY (gonadal soma derived...
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