Insulin-like growth factor binding protein-3 (IGFBP-3) genetic variant and the risk of esophageal squamous cell carcinoma in a Chinese population.

doi:10.4238/2014.May.30.10

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Insulin-like growth factor binding protein-3 (IGFBP-3) genetic variant and the risk of esophageal squamous cell carcinoma in a Chinese population.

Genetics and molecular research : GMR - 30 May 2014

Yang H-P, Liu J-F, Rao J, Zhang X-M, Qian H-L, Niu X-Q, Zhao Z-L

Abstract excerpt

Insulin-like growth factor binding protein-3 (IGFBP-3) exerts anti-proliferative or pro-apoptotic effects through IGF-dependent as well as IGF-independent mechanisms in vitro. The purpose of this study was to examine the association between genetic variants in IGFBP-3 (rs2270628) and the risk of esophageal squamous cell carcinoma (ESCC) in a Chinese Han population. Five hundred ESCC cases and 500 cancer-free...

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PMID: 24938707
DOI: 10.4238/2014.May.30.10

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