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Article

Single nucleotide polymorphisms of IGFBP-3 gene and lung cancer risk in a Korean population.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2008

Han Sle Gi Lo, Park Kyong Hwa, Sung Jae Sook, Whang Young Mi, Kim Yeon Jung, Shin Eun Soon, Lee Jae Won, Lee Hyo Jung, Ryu Jeong-Seon, Choi In Keun, Seo Jae Hong, Kim Yeul Hong

Abstract excerpt

Insulin-like growth factor binding protein-3 (IGFBP-3) is a putative tumor suppressor and inhibits the mitogenic and antiapoptotic activity of insulin-like growth factor (IGF) by blocking the binding to its receptors or by IGF-independent manner. Epidemiological studies have suggested that serum level of IGFBP-3 is associated with lung cancer risk. The present study was conducted to evaluate the association...

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Identifiers

PMID: 18450319
DOI: 10.1016/j.lungcan.2008.03.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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