Article
The role of IGFBP3 functional polymorphisms in the risk of gastric cancer in a high-risk Chinese population.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Apr 2008
Chen Wensen, Wang Lina, Ke Qiao, Jin Guangfu, Tan Yongfei, Zhou Yan, Hu Zhibin, Ma Hongxia, Wang Jianmin, Hua Zhaolai, Ding Weiliang, Shen Jing, Xu Yaochu, Shen Hongbing
Abstract excerpt
Insulin-like growth factors (IGFs) and their receptors play a crucial role in regulating cell proliferation, differentiation, and apoptosis. Insulin-like growth factor-binding protein-3 is the most abundant insulin-like growth factor receptor in the serum and binds the majority of insulin-like growth factors. Studies reported that circulating level of insulin-like growth factor-binding protein-3 was modulated by...
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