Further evidence that methylenetetrahydrofolate reductase A1298C polymorphism is a risk factor for schizophrenia.

doi:10.1007/s00702-010-0442-3

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Further evidence that methylenetetrahydrofolate reductase A1298C polymorphism is a risk factor for schizophrenia.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2010

Zhang Chen, Xie Bin, Du Yasong, Cheng Wenhong, Fang Yiru, Yu Shunying

Abstract excerpt

Previous work suggests that the methylenetetrahydrofolate reductase gene (MTHFR) functional polymorphism A1298C may be a risk factor for schizophrenia. In this study, the genetic association between the MTHFR A1298C polymorphism and schizophrenia was investigated in 379 patients with schizophrenia and 380 age- and sex-matched controls subjects. The results showed an association between the 1298C allele and the...

Topics

Adult
Asian People
Chi-Square Distribution
Female
Gene Frequency
Genetic Predisposition to Disease
Humans
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Single Nucleotide
Risk Factors
Schizophrenia

Source

Open in PubMed

Identifiers

PMID: 20694488
DOI: 10.1007/s00702-010-0442-3

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics