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Article

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia.

NeuroImage. Clinical - 1 Jan 2014

Majid Tabassum, Ali Yousuf O, Venkitaramani Deepa V, Jang Ming-Kuei, Lu Hui-Chen, Pautler Robia G

Abstract excerpt

BACKGROUND: Axonal transport is vital for neurons and deficits in this process have been previously reported in a few mouse models of Alzheimer's disease prior to the appearance of plaques and tangles. However, it remains to be determined whether axonal transport is defective prior to the onset of neurodegeneration. The rTg4510 mouse, a fronto-temporal dementia and parkinsonism-17 (FTDP-17) tauopathy model,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24936422
DOI: 10.1016/j.nicl.2014.02.005
PMCID: PMC4053640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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