Article
Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI).
NeuroImage - 1 Jan 2007
Bearer Elaine L, Falzone Tomás Luis, Zhang Xiaowei, Biris Octavian, Rasin Arkady, Jacobs Russell E
Abstract excerpt
MEMRI offers the exciting possibility of tracing neuronal circuits in living animals by MRI. Here we use the power of mouse genetics and the simplicity of the visual system to test rigorously the parameters affecting Mn2+ uptake, transport and trans-synaptic tracing. By measuring electrical response to light before and after injection of Mn2+ into the eye, we determine the dose of Mn2+ with the least toxicity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
