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Article

Genotype-guided vs clinical dosing of warfarin and its analogues: meta-analysis of randomized clinical trials.

JAMA internal medicine - 1 Aug 2014

Stergiopoulos Kathleen, Brown David L

Abstract excerpt

IMPORTANCE: Significant variations in dose requirements of warfarin and its analogues (acenocoumarol and phenprocoumon) make selecting the appropriate dose for an individual patient difficult. Genetic factors account for approximately one-third of the variation in dose requirement. The clinical usefulness of genotype-guided dosing of warfarin has been previously assessed in randomized clinical trials that were...

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Source

Identifiers

PMID: 24935087
DOI: 10.1001/jamainternmed.2014.2368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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