Article
Pharmacogenetics-Based versus Conventional Dosing of Warfarin: A Meta-Analysis of Randomized Controlled Trials.
PloS one - 1 Jan 2015
Shi Changcheng, Yan Wei, Wang Gang, Wang Fei, Li Qingyu, Lin Nengming
Abstract excerpt
BACKGROUND: Recently, using the patient's genotype to guide warfarin dosing has gained interest; however, whether pharmacogenetics-based dosing (PD) improves clinical outcomes compared to conventional dosing (CD) remains unclear. Thus, we performed a meta-analysis to evaluate these two strategies. METHODS: The PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chinese VIP and...
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