Article
Warfarin pharmacogenetics: to genotype or not to genotype, that is the question.
Clinical pharmacology and therapeutics - 1 Jul 2014
Cavallari L H, Nutescu E A
Abstract excerpt
Genotype is well recognized to influence the dose of warfarin necessary for therapeutic anticoagulation. Recent randomized controlled trials evaluating the clinical utility of genotype-guided warfarin dosing have produced varying results. We review the design and results of the recent clinical trials, assess the impact of their findings on warfarin dosing, and examine unanswered questions related to clinical...
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