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Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease.

Gastroenterology - 1 Sept 2014

Dhillon Sandeep S, Fattouh Ramzi, Elkadri Abdul, Xu Wei, Murchie Ryan, Walters Thomas, Guo Conghui, Mack David, Huynh Hien Q, Baksh Shairaz, Silverberg Mark S, Griffiths Anne M, Snapper Scott B, Brumell John H, Muise Aleixo M

Abstract excerpt

BACKGROUND & AIMS: The colitis observed in patients with very early onset inflammatory bowel disease (VEOIBD; defined as onset of disease at younger than 6 years of age) often resembles that of chronic granulomatous disease (CGD) in extent and features of colonic inflammation observed by endoscopy and histology. CGD is a severe immunodeficiency caused by defects in the genes that encode components of the...

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PMID: 24931457
DOI: 10.1053/j.gastro.2014.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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