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Article

Genomic and Immunologic Drivers of Very Early-Onset Inflammatory Bowel Disease

6 Mar 2019

Abstract excerpt

PURPOSE OF REVIEW: Inflammatory bowel disease (IBD) is a multifactorial disease caused by dysregulated immune responses to commensal or pathogenic intestinal microbes, resulting in chronic intestinal inflammation. However, a subset of patients with IBD diagnosed <6 years of age, known as very early-onset (VEO)-IBD, can be phenotypically and genetically distinct from older onset IBD. We aim to review the clinical...

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PMID: 30841788
DOI: 10.1177/1093526619834807

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