Article
The Growing Need to Understand Very Early Onset Inflammatory Bowel Disease.
Frontiers in immunology - 1 Jan 2021
Zheng Hengqi B, de la Morena M Teresa, Suskind David L
Abstract excerpt
Very Early Onset Inflammatory Bowel Disease (VEO-IBD) represents a cohort of inflammatory bowel disease (IBD) patients diagnosed before 6 years of age. Unlike IBD diagnosed at older ages, VEO-IBD can be associated with underlying primary immunodeficiencies. VEO-IBD has been linked to monogenic variations in over 70 genes involved in multiple pathways of immunity. As sequencing technologies and platforms evolve...
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