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Article

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.

Proceedings of the National Academy of Sciences of the United States of America - 17 Jun 2014

Mahdessian Hovsep, Taxiarchis Apostolos, Popov Sergej, Silveira Angela, Franco-Cereceda Anders, Hamsten Anders, Eriksson Per, van't Hooft Ferdinand

Abstract excerpt

Genome-wide association studies have identified a locus on chromosome 19 associated with plasma triglyceride (TG) concentration and nonalcoholic fatty liver disease. However, the identity and functional role of the gene(s) responsible for these associations remain unknown. Of 19 expressed genes contained in this locus, none has previously been implicated in lipid metabolism. We performed gene expression studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24927523
DOI: 10.1073/pnas.1323785111
PMCID: PMC4066487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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