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Article

Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis.

PloS one - 1 Jan 2013

Bolin Karin, Sandling Johanna K, Zickert Agneta, Jönsen Andreas, Sjöwall Christopher, Svenungsson Elisabet, Bengtsson Anders A, Eloranta Maija-Leena, Rönnblom Lars, Syvänen Ann-Christine, Gunnarsson Iva, Nordmark Gunnel

Abstract excerpt

Lupus nephritis is a cause of significant morbidity in systemic lupus erythematosus (SLE) and its genetic background has not been completely clarified. The aim of this investigation was to analyze single nucleotide polymorphisms (SNPs) for association with lupus nephritis, its severe form proliferative nephritis and renal outcome, in two Swedish cohorts. Cohort I (n = 567 SLE cases, n = 512 controls) was...

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Share to Lupus Nephritis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

Share to Severity of Illness Index

Share to STAT4 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 24386384
DOI: 10.1371/journal.pone.0084450
PMCID: PMC3873995

Genes

STAT4
BLK
TNIP1
CARD11
IRAK1
ITGAM
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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