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Article

L-type calcium channel modulates cystic kidney phenotype.

Biochimica et biophysica acta - 1 Sept 2014

Jin Xingjian, Muntean Brian S, Aal-Aaboda Munaf S, Duan Qiming, Zhou Jing, Nauli Surya M

Abstract excerpt

In polycystic kidney disease (PKD), abnormal proliferation and genomic instability of renal epithelia have been associated with cyst formation and kidney enlargement. We recently showed that L-type calcium channel (CaV1.2) is localized to primary cilia of epithelial cells. Previous studies have also shown that low intracellular calcium level was associated with the hyperproliferation phenotype in the epithelial...

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Identifiers

PMID: 24925129
DOI: 10.1016/j.bbadis.2014.06.001
PMCID: PMC4125496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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