Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Recent advances in molecular pathogenesis and treatment of polycystic kidney disease].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 1 Jan 2000

Covic M, Covic Maria

Abstract excerpt

Polycystic kidney diseases (PKD) are common genetic disorders characterized by formation and progressive enlargement of cysts kidney, liver and other organs, leading to end stage renal disease. Regardless of the genetic defect underlying PKD, cystic epithelia seem to display common abnormalities: increased proliferation and apoptosis, loss of cellular differentiation and polarity, hypersecretion. The localization...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protein Kinases
Share to Cyclic AMP
Share to Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinases

Share to Polycystic Kidney Diseases

Share to Receptors, Cell Surface

Share to TOR Serine-Threonine Kinases

Share to TRPP Cation Channels

Source

Identifiers

PMID: 18677899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Recent advances in molecular pathogenesis and treatment of polycystic kidney disease].PMID 18677899Read ↗

Polycystic kidney diseases: from molecular discoveries to targeted therapeutic strategies.Semantic proximity Read ↗

Molecular pathways and therapies in autosomal-dominant polycystic kidney disease.Semantic proximity Read ↗

Molecular and cellular pathogenesis of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

mTOR signaling in polycystic kidney disease.Semantic proximity Read ↗

Polycystic Kidney DiseaseSemantic proximity Read ↗

Diagnosis, pathogenesis, and treatment prospects in cystic kidney disease.Semantic proximity Read ↗

[Pathophysiology, epidemiology, clinical presentation, diagnosis and treatment options for autosomal dominant polycystic kidney disease].Semantic proximity Read ↗

Physiologic mechanisms underlying polycystic kidney disease.Semantic proximity Read ↗

Autosomal dominant polycystic kidney disease: Disrupted pathways and potential therapeutic interventions.Semantic proximity Read ↗

Therapeutic targets for polycystic kidney disease.Semantic proximity Read ↗

Genetics and Pathogenesis of Polycystic Kidney DiseaseSemantic proximity Read ↗

Targeting new cellular disease pathways in autosomal dominant polycystic kidney diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.