Article
Human Longevity is Influenced by Many Genetic Variants: Evidence from 75,000 UK Biobank Participants
2016-02-01
Abstract excerpt
Variation in human lifespan is 20 to 30% heritable but few genetic variants have been identified. We undertook a Genome Wide Association Study (GWAS) using age at death of parents of middle-aged UK Biobank participants of European decent (n=75,244 with father’s and/or mother’s data). Genetic risk scores for 19 phenotypes (n=777 proven variants) were also tested. Genotyped variants (n=845,997) explained 10.2% (SD=1...
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Identifiers and source
- Literature Corpus work
- 05dda0d9-f962-5dd5-b8d6-a4a2733160f4
- DOI
- 10.1101/038430