Article
Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae.
Genetics - 1 Aug 2014
Li Tianlu, Belda-Palazón Borja, Ferrando Alejandro, Alepuz Paula
Abstract excerpt
eIF5A is an essential and evolutionary conserved translation elongation factor, which has recently been proposed to be required for the translation of proteins with consecutive prolines. The binding of eIF5A to ribosomes occurs upon its activation by hypusination, a modification that requires spe...
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