Article
The F-BAR protein Hof1 tunes formin activity to sculpt actin cables during polarized growth.
Molecular biology of the cell - 1 Jun 2014
Graziano Brian R, Yu Hoi-Ying E, Alioto Salvatore L, Eskin Julian A, Ydenberg Casey A, Waterman David P, Garabedian Mikael, Goode Bruce L
Abstract excerpt
Asymmetric cell growth and division rely on polarized actin cytoskeleton remodeling events, the regulation of which is poorly understood. In budding yeast, formins stimulate the assembly of an organized network of actin cables that direct polarized secretion. Here we show that the Fer/Cip4 homology-Bin amphiphysin Rvs protein Hof1, which has known roles in cytokinesis, also functions during polarized growth by...
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