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Article

eIF5A has a function in the elongation step of translation in yeast.

Biochemical and biophysical research communications - 20 Mar 2009

Gregio Ana P B, Cano Veridiana P S, Avaca Juliana S, Valentini Sandro R, Zanelli Cleslei F

Abstract excerpt

The putative translation factor eIF5A is essential for cell viability and is highly conserved throughout evolution. Here, we describe genetic interactions between an eIF5A mutant and a translation initiation mutant (eIF4E) or a translation elongation mutant (eEF2). Polysome profile analysis of single and double mutants revealed that mutation in eIF5A reduces polysome run-off, contrarily to translation initiation...

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Source

Identifiers

PMID: 19338753
DOI: 10.1016/j.bbrc.2009.01.148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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