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Article

Sensitive allele-specific real-time PCR test for mutations in BRAF codon V600 in skin melanoma.

Melanoma research - 1 Aug 2014

Pisareva Ekaterina, Gutkina Nadezhda, Kovalenko Sergei, Kuehnapfel Sarah, Hartmann Arndt, Heinzerling Lucie, Schneider-Stock Regine, Lyubchenko Lyudmila, Shamanin Vladimir A

Abstract excerpt

Mutations at BRAF codon V600 are used as predictive biomarkers for targeted therapy of skin melanoma. Here, a simple sensitive test to detect mutations of BRAF-V600 was developed using real-time PCR with allele-specific primers and TaqMan probes. Two versions of the test using sense and antisense...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24922189
DOI: 10.1097/CMR.0000000000000090

Genes

BRAF
GAA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24922189-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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