Article
The \textit{BRAF} V600E mutation in single- institution study of Russian melanoma patients.
Cancer biomarkers : section A of Disease markers - 1 Jan 2016
Lyubchenko Ludmila, Emelyanova Marina, Shamanin Vladimir, Demidov Lev, Zasedatelev Alexander, Nasedkina Tatyana
Abstract excerpt
BACKGROUND: The activating mutation BRAF V600E is considered to be a diagnostic cutaneous melanoma (CM) marker important for prognosis and targeted therapy. OBJECTIVE: The aim of this study was to determine the frequency of the V600E mutation in CM patients in Russia and to estimate the influence of the BRAF gene mutation status on prognosis and clinical outcome. METHODS: To ensure mutation detection in FFPE...
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