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Article

A Sensitive Peptide Nucleic Acid Probe Assay for Detection of BRAF V600 Mutations in Melanoma.

Cancer genomics & proteomics - 1 Jan 2000

Chen Tai-Long, Chang John Wen-Cheng, Hsieh Jia-Juan, Cheng Hsin-Yi, Chiou Chiuan-Chian

Abstract excerpt

Mutated v-Raf murine sarcoma viral oncogene homolog B (BRAF) is an important biomarker for the prediction of therapeutic efficacy of several anticancer drugs. The detection of BRAF mutation faces two challenges: Firstly, there are multiple types of mutations, and secondly, tumor samples usually contain various amounts of wild-type, normal tissues. Here, we describe a newly established method for sensitive...

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Share to Peptide Nucleic Acids
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

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Share to Polymerase Chain Reaction

Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 27566656
PMCID: PMC5070627

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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