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Article

Prognostic significance of CD44 variant 2 upregulation in colorectal cancer

12 Jun 2014

Abstract excerpt

BACKGROUND: CD133 and CD44 are putative cancer stem cell (CSC) markers in colorectal cancer (CRC). However, their clinical significance is currently unclear. Here, we evaluated primary CRC cell isolates to determine the significance of several CSC markers, including CD133 and CD44, as predictors of tumourigenesis and prognosis. METHODS: CD133- and CD44-positive cells from fresh clinical samples of 77 CRCs were...

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PMID: 24921913
DOI: 10.1038/bjc.2014.253

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