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Article

Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker

20 Mar 2012

Abstract excerpt

BACKGROUND: Isolation and characterization of tumourigenic colon cancer initiating cells may help to develop novel diagnostic and therapeutic procedures. METHODS: We characterized a panel of fourteen human colon carcinoma cell lines and their corresponding xenografts for the surface expression of potential stem cell markers CD133, CD24, CD44, CDCP1 and CXCR4. In five cell lines and nine xenografts, mRNA...

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PMID: 22433494
DOI: 10.1186/1471-2407-12-96

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