Article
Cancer Stem Cell Gene Variants in CD44 Predict Outcome in Stage II and Stage III Colon Cancer Patients.
Anticancer research - 1 Apr 2017
Stotz Michael, Herzog Sereina A, Pichler Martin, Smolle Maria, Riedl Jakob, Rossmann Christopher, Bezan Angelika, Stöger Herbert, Renner Wilfried, Berghold Andrea, Gerger Armin
Abstract excerpt
BACKGROUND/AIM: Growing evidence suggests that human cancers are stem cell diseases and recent data support the existence of cancer stem cells (CSCs) in a variety of malignancies, including colon cancer. These CSCs were shown to be capable of initiating tumor development and progression. Several studies have suggested CD133, CD26 and CD44 as markers of tumor-initiating cells of colon cancer. The purpose of the...
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