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Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis.

Cancer genomics & proteomics - 1 Jan 2000

Botchkina Inna L, Rowehl Rebecca A, Rivadeneira David E, Karpeh Martin S, Crawford Howard, Dufour Antoine, Ju Jingfang, Wang Yuan, Leyfman Yan, Botchkina Galina I

Abstract excerpt

BACKGROUND: Human cancer is characterized by high heterogeneity in gene expression, varieties of differentiation phenotypes and tumor-host interrelations. Growing evidence suggests that tumor-initiating, or cancer stem cells (CSCs), may also represent a heterogeneous population. The present study was undertaken to isolate and characterize the different phenotypic subpopulations of metastatic colon cancer and to...

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PMID: 19451087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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