CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines.

doi:10.5966/sctm.2012-0003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines.

Stem cells translational medicine - 1 Aug 2012

Muraro Manuele Giuseppe, Mele Valentina, Däster Silvio, Han Junyi, Heberer Michael, Cesare Spagnoli Giulio, Iezzi Giandomenica

Abstract excerpt

Increasing evidence that cancers originate from small populations of so-called cancer stem cells (CSCs), capable of surviving conventional chemotherapies and regenerating the original tumor, urges the development of novel CSC-targeted treatments. Screening of new anticancer compounds is conventionally conducted on established tumor cell lines, providing sufficient material for high-throughput studies. Whether...

Topics

AC133 Antigen
Activated-Leukocyte Cell Adhesion Molecule
Aldehyde Dehydrogenase 1 Family
Animals
Antigens, CD
Antimetabolites, Antineoplastic
Biomarkers, Tumor
CD24 Antigen
Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fluorouracil

Glycoproteins

Humans

Hyaluronan Receptors

Isoenzymes

Mice

Mice, Inbred NOD

Mice, SCID

Neoplastic Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 23197865
DOI: 10.5966/sctm.2012-0003
PMCID: PMC3659731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines.PMID 23197865Read ↗

Colorectal Cancer Stem Cell Biomarkers: Biological Traits and Prognostic InsightsSemantic proximity Read ↗

The requirement for freshly isolated human colorectal cancer (CRC) cells in isolating CRC stem cellsSemantic proximity Read ↗

Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy ResistanceSemantic proximity Read ↗

Phenotypic characterization of human colorectal cancer stem cells.Semantic proximity Read ↗

Establishment of Highly Tumorigenic Human Colorectal Cancer Cell Line (CR4) with Properties of Putative Cancer Stem CellsSemantic proximity Read ↗

Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis.Semantic proximity Read ↗

Molecular identification and targeting of colorectal cancer stem cellsSemantic proximity Read ↗

Deciphering biological characteristics of tumorigenic subpopulations in human colorectal cancer reveals cellular plasticitySemantic proximity Read ↗

CD133 as a target for colon cancerSemantic proximity Read ↗

Cancer stem cells in colorectal cancer from pathogenesis to therapy: Controversies and perspectivesSemantic proximity Read ↗

Characterization of CD44-positive Cancer Stem-like Cells in COLO 201 CellsSemantic proximity Read ↗

Cancer Stem Cell Markers in Relation to Patient Survival Outcomes: Lessons for Integrative Diagnostics and Next-Generation Anticancer Drug DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.