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Article

Filaggrin gene mutations in African Americans with both ichthyosis vulgaris and atopic dermatitis.

Pediatric dermatology - 1 Jan 2000

Polcari Ingrid, Becker Lauren, Stein Sarah L, Smith Marilyn S, Paller Amy S

Abstract excerpt

Atopic dermatitis (AD) and ichthyosis vulgaris (IV) are two common disorders of epidermal homeostasis resulting in dry skin. The profilaggrin gene, located on chromosome 1q22, encodes a keratin filament aggregating protein (filaggrin) that is essential to forming the epidermal barrier and maintai...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24920311
DOI: 10.1111/pde.12355

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24920311-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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