Article
Acquired initiating mutations in early hematopoietic cells of CLL patients.
Cancer discovery - 1 Sept 2014
Damm Frederik, Mylonas Elena, Cosson Adrien, Yoshida Kenichi, Della Valle Véronique, Mouly Enguerran, Diop M'boyba, Scourzic Laurianne, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Kikushige Yoshikane, Davi Frederick, Lambert Jérôme, Gautheret Daniel, Merle-Béral Hélène, Sutton Laurent, Dessen Philippe, Solary Eric, Akashi Koichi, Vainchenker William, Mercher Thomas, Droin Nathalie, Ogawa Seishi, Nguyen-Khac Florence, Bernard Olivier A
Abstract excerpt
UNLABELLED: Appropriate cancer care requires a thorough understanding of the natural history of the disease, including the cell of origin, the pattern of clonal evolution, and the functional consequences of the mutations. Using deep sequencing of flow-sorted cell populations from patients with ch...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.