Article
Chronic lymphocytic leukemia: Time to go past genomics?
American journal of hematology - 1 May 2016
Roos-Weil Damien, Nguyen-Khac Florence, Bernard Olivier A
Abstract excerpt
Recent advances in massively parallel sequencing technologies have provided a detailed picture of the mutational landscape in CLL and underscored the vast degree of interpatient and intratumor heterogeneities. These studies have led to the characterization of novel putative driver genes and recurrently affected biological pathways, and to the modeling of CLL clonal evolution. We herein review selected aspects...
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