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Article

Fibulin-5 (FBLN5) gene polymorphism is associated with pelvic organ prolapse.

Maturitas - 1 Aug 2014

Khadzhieva Maryam B, Kamoeva Svetlana V, Chumachenko Anastasya G, Ivanova Anastasya V, Volodin Ilya V, Vladimirov Ivan S, Abilev Serikbay K, Salnikova Lyubov E

Abstract excerpt

OBJECTIVE: FBLN5 encodes a key protein of elastic fiber matrix assembly and function that contributes to maintaining pelvic support and plays the important role in the pathophysiology of pelvic organ prolapse (POP). The aim of the study was to investigate whether there is an association between common single-nucleotide polymorphisms (SNPs) of the FBLN5 gene and POP. STUDY DESIGN: A total of eleven tag SNPs of the...

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PMID: 24917111
DOI: 10.1016/j.maturitas.2014.05.003

Genes

FBLN5

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