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Article

Role of fibulin-5 insufficiency and prolapse progression on murine vaginal biomechanical function

25 Oct 2021

Abstract excerpt

The vagina plays a critical role in supporting the pelvic organs and loss of support leads to pelvic organ prolapse. It is unknown what microstructural changes influence prolapse progression nor how decreased elastic fibers contributes to vaginal remodeling and smooth muscle contractility. The objective for this study was to evaluate the effect of fibulin-5 haploinsufficiency, and deficiency with progressive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34697337
DOI: 10.1038/s41598-021-00351-1

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