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Article

Interactions between genetic variants and environmental risk factors are associated with the severity of pelvic organ prolapse.

Menopause (New York, N.Y.) - 1 Jun 2023

Li Lei, Zhao Guangyi, Wu Jie, Pang Haiyu, Zhang Tianli, Chen Juan, Zhang Kunlin, Zhu Lan

Abstract excerpt

OBJECTIVE: Both environmental and genetic risk factors contribute to pelvic organ prolapse (POP). No genome-wide study has investigated the gene-environment (G × E) interactions. In this study, we aim to identify single nucleotide polymorphisms (SNPs) that may interact with the potential environmental factors, maximum birth weight, and age in Chinese women. METHODS: We recruited 576 women for phase 1 and 264...

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PMID: 37040585
DOI: 10.1097/GME.0000000000002182
PMCID: PMC10227931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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